Résumé
Coronavirus disease-19 (COVID-19) pandemic is a real challenge to our communities worldwide, exerting a high socioeconomic impact. The disease is associated with a great deal of co-agulation cascade disorder, with a considerable increase in D-dimer concentration in blood. Objec-tives: To assess the impact of dialysis session frequency on blood levels of D-dimer among CKD patients infected with COVID-19. Patients and Methods: The study included 40 CKD patients (22 males and 18 females) infected with COVID-19, who attended the Artificial Kidney Unit at Al Hussein Teaching Hospital, Thi-Qar, Iraq for regular dialysis. They were divided into two groups;Group I: 20 CKD patients who had COVID-19. They underwent one hemodialysis session per week. The second group, which included 20 CKD patients infected with COVID-19 underwent three dialysis sessions per week. Plasma levels of D-dimer were measured one day before the start of the study and one day after three weeks in both groups. Result(s): The results of the present study re-vealed that CKD patients infected with COVID-19 who underwent three dialysis session per week (Group II) had a significant drop in blood D-dimer level at the end of three weeks in comparison to the initial values. Furthermore, the decrease in blood D-dimer level was significantly higher among CKD patients with COVID-19 who underwent three dialysis sessions per week (Group II) in comparison to COVID-19 infected CKD patients who underwent single dialysis sessions per week (Group I). Conclusion(s): CKD patients with COVID-19 have an elevated blood level of D-dimer. Increasing the frequency of hemodialysis plays an essential role in lowering the serum D-dimer level among these patients.Copyright © 2023, Colegio de Farmaceuticos de la Provincia de Buenos Aires. All rights reserved.
Résumé
The first confirmed COVID-19 case reported in Iraq was in Najaf Governorate on February 2020. Soon later, Iraqi cities have witnessed a significant increase in the reported cases;among them is Diwaniya city in which 13246 total cases were reported on the 25th of September 2020. The cure rate was about 78% (169 deaths and 10676 recovered patients). De-spite the healthcare interventions performed by the medical staff, particularly the public health authorities in Diwaniya city, there have been a dramatically increasing number of reported cas-es. This work aims at introducing comprehensive study and epidemiological characterization of COVID-19 reported cases in Diwaniya governorate. The study involve descriptive analysis of COVID-19 confirmed cases reported in Diwaniya Governorate (24 February 2020 to 25 September 2020). The anal ysi s i nvol ved epi demi ol ogi cal and demographi c characteri zati on of confirmed cases. Data were kindly obtained from the Directorate of Health in Diwaniya. Results and discussion: The highest prevalence was reported in the city center followed by Shamyah district, Al-Hamza district and Afak district, respectively. In terms of gender, about 48% of the confirmed patients were females and about 52% were males (with death rate of about 1.4% 1.8% in females and males, respectively). Although the age in most cases was between 20 and 60 years, the highest incidence (20%) was in age of 30 to 40years. In addition, 8%of reported cases were in children under 15 years old. About 5% of cases were among healthcare workers. Highlighting such findings can enable the community to understand and reconsider COVID-19 spread in Diwaniya, increase the awareness of our community and establish a baseline data for future studies.